Do you get angry inside every time your best friend refuses a piece of cake after eating a salad? Do you think nature is poorly made? There is something to stir up jealousy, indeed, but also something to work on letting go. Two new studies reported by the New York Times indicate that the controlling our weight is more often the result of genetics than of our will.
So there are biological reasons for which some people lconstantly with their weight and not others. The gene in question, called MC4R, would have a impact on appetite, not on metabolism. About 6% of the population is believed to be the carrier of mutations in this gene. People who gain too much weight or find it difficult to stay lean , therefore, feel more hungry than “naturally” thin people, in whom the gene is continuously activated.
Cut or increase appetite
The participants of the first study, published by the journal Cell, had been thin all their life. They didn’t have an unusual metabolism but just didn’t care much about food. They never ate too much, and never thought anxiously about the “next meal”. The study determined the presence of a genetic alteration that suppresses appetite, and at the same time reduces the risk of diabetes and heart disease.
A second study also published by Cell, used the same data to establish a genetic risk score for obesity. Scientists at Cambridge University in the UK have found that some people carry a rare mutation in the MC4R gene. which prevents it from functioning. They observed up to 300 possible genetic mutations, responsible for obesity, which prevent the feeling full After a meal. Their body never gets the signal that they have eaten enough. This new track constitutes an obvious target of drugs for overweight people.