In a study published in the specialized journal Circulation, researchers at Massachusetts General Hospital (MGH, United States), report observing that about 12 minutes ofcardio-respiratory exercises had a significant impact on metabolism. More specifically, this short session of physical activity took a positive impact on more than 80% of circulating metabolites, in particular metabolites involved in insulin resistance (glutamate for example) and in lipolysis, in other words fat burning.
Clear, no need to work out for hours to see metabolic health benefits, and thus reduce, even slightly, his risk of overweight, diabetes or prediabetes. Gregory Lewis, Director of the Heart Failure Center at the MGH and co-author of the study, commented:
“What struck us were the effects a brief exercise can have on circulating levels of metabolites that govern key bodily functions such as insulin resistance, the oxidative stress, lhas vascular reactivity, inflammation and longevity. “
The study here was based on data from the Framingham Heart Study and consisted of measuring the blood levels of 588 metabolites before and immediately after approximately 12 minutes of high intensity sport, in 411 participants. The sample consisted of 63% of women and people between 45 and 61 years old. The research team then detected changes for 502 out of 588 metabolites, and for which the levels measured at rest were associated with cardiometabolic pathologies (diabetes, cardiac pathology, etc.).
The researchers cite in particular the glutamate, a metabolite linked to diabetes, cardiovascular disease and reduced longevity, a metabolite whose blood concentration fell by 29% after exercising. Another example, that of “Dimethyl Guanidino Valeric acid” or DMGV, a metabolite linked to an increased risk of diabetes and liver disease, the concentration of which fell by 18%. The study also showed that other key factors, such as gender and body mass index (BMI), could somehow slow down benefits of exercise on metabolism.
Besides the fact that it invites to exercise, even for a short duration, this study reveals that the blood concentration of several metabolics can be a good indicator of an individual’s physical form, in the same way that blood tests can tell us about healthy liver or kidneys, the researchers say. “For example, low levels of DMGV can mean that the individual has a strong physical activity”, commented Matthew Nayor, co-author of the study.